M.Z.Segal ??? ??? ?? ??? Tatarstan ??? ???? ??? ?? ?? ??? ??? ??? Dr. Hasanov Marat Zufarovich ???? ??????.
???, ?????(nodular pathology), ????????(TRUS), ????? ??(Strain Elastography mode), ???????(CEUS)
?
66? ??? ??? ?? ??? ???? ??? ???? ??????(VASH 5 ??? ??). ??? PSA ??? 6.9 ng/ml??? ????? ???? ??? ??? ??? ??? ?????.
????? Resona 7 ??? ??? ??? ??? ??? ??(TRUS)? ??????. ???? ??? 36ml? ??????, ??? ??(interlobular furrow) ?? ??(right lobe) ????? ?? ?? 15mm? ????? ???? ??? ??? ??? ???????(Fig. 1).
?? ??? ??, B-?? TRUS ???? ??? ?? ??? ????? ??(vascularity) ??? ???????(?? 2).
Resona7? Natural Touch Elastography? ???? ???? ??? ??????. ?? ??? ??? ??? 0.56-0.87 ??? ???? ?? ???? ?? ? ??? ??? ???? ?????.
???? ???(CEUS)? ??, ?????? 2.4ml? Sonovue(Bracco Swiss, SA, Switzerland)? 3? ?? ??? ?? ?? ??? ????????. ???? ??? ??? ???? ?? ??, ??? ?? ????? ??? ?? ??(parenchyma)? ??? ????? ?????(??. 4).
?? ??? ??-?? ??? ??? ??? ?? ?? ??? ??? ???? ???. ?? ??? ??? TTP 16.5?, PI 35.7dB, DT/2 78.6?, AUC 4634.2dB/? ????. ???? ?? ?? ??? ?? ??-?? ??? ???? ?? ? ?? ??? ??? ???? ??? TTP? 63.9?, PI? 27.5dB, AUC? 4429.2dB/? ????. DT/2 ????? ???? ?????(??? 5).
???? ???? ???(transrectal) ??? ??? ???? 12? ??? ?? ????? ???????.
?
???? ??: ?? ??? ?? ???? ???(acinar adenocarcinoma )? ??? Gleason(3 + 4)? ?? 7????. ?? ?? ??? ?? ??? ???? ??, ???? ?? ???? ?? ??? ?? ???? ?????. (?? 6).
???? ?? ??(Malignant ?neoplasm), T2сsN0M0.
????? ???? ??? ??? ??? ??? ?? ?? ???? ???, ??? (hypervascular )???? ?????[1]. ??? ??? ??? ?? ??? ??? ??? ??? ? ?? ??? ???? ?? ?? ?????[2]. ?? ???? ?? ?? ??? ???? ?? ??? ???(multiparametric ultrasound )? ?????. ?????(Strain elastography )? ??? ?? ???? ?? ??? ??? ??? ? ????. ?? ??? ?? ???? ? ??? ??? ???, ?? ??? ?? ??? ?? ??? ?? ??? ??? ??? ??? ???? ?? ? ??? ???? ? ? ??? ?? ?? ?? ????. CEUS? ?? ??? ???? ? ??? ??? ??? ? ????. ? ??, CEUS ??? B ?? ???? ??? ?? ?? ? ???? ????? ??? ???? ??? ??? ????? ?? ???????.
??:
[1] Ellis, W. J., Chetner, M. P., Preston, S. D. & Brawer, M. K., 1994. Diagnosis of Prostatic Carcinoma: The Yield of Serum Prostate Specific Antigen, Digital Rectal Examination and Transrectal Ultrasonography. The Journal of Urology, 152(5, part 1), pp. 1520-1525.
[2]?Postera, A., Mischi, M., Rosette, J. d. l. & Wijkstra, H., 2015. Multiparametric ultrasound in the detection of prostate cancer: a systematic review. World Journal of Urology, 33(11), pp. 1651-1659.